In the premium sectors of fine perfumery, luxury cosmetics, functional skincare, and personal care, sclareolide (CAS 564-20-5) stands out as a multifunctional, 100% naturally derived diterpene lactone. Renowned for its warm, woody-amber fragrance profile—featuring deep amber-musk, balsamic, slightly sweet, and long-lasting woody nuances—sclareolide delivers exceptional fixative properties that stabilize volatile top and middle notes, prolong scent longevity, and enhance overall depth and elegance in compositions.
Often used as a sustainable alternative to traditional ambergris derivatives, sclareolide imparts a rich, velvety dry-down with subtle tobacco-like warmth and herbal undertones, making it ideal for amber, woody, oriental, musk, and gourmand accords in high-end perfumes, colognes, and functional fragrances.
Exceptional Fragrance Fixation and Multifunctional Bioactive Power
With its molecular formula C₁₆H₂₈O and high ≥98% purity, sclareolide ensures clean, consistent performance with minimal impurities and maximum efficacy:
- In fine fragrances and personal care: Acts as a powerful base note and fixative, extending fragrance duration in perfumes, body sprays, deodorants, soaps, and lotions—substantivity up to 108 hours in dilution.
- In skincare formulations: Offers clinically relevant bioactive benefits, including potent inhibition of UV-induced pigmentation and melanin synthesis for anti-photoaging and brightening effects; promotes even, radiant complexion with secondary photoprotective support.
- In hair and scalp care: Reduces scalp inflammation, rebalances the microbiome, limits Malassezia fungi growth (linked to dandruff), and soothes irritation—addressing visible flakes, redness, and underlying causes for healthier scalp desquamation.
Skincare – Brightening & UV Protection
- Mechanism: Strongly inhibits melanin production and UV-triggered hyperpigmentation pathways.
- Recommended Usage: 0.1–0.2% in facial serums, creams, moisturizers, and sun care products.
- Formulation Notes: White powder, oil-soluble; excels in emulsions and oil-based systems.
- Key Benefits: Evens skin tone, reduces dark spots, enhances radiance, and provides gentle photoprotection.
Hair & Scalp Care – Anti-Dandruff & Soothing
- Mechanism: Modulates inflammation, supports microbiome balance, and activates vitamin D-related functions for scalp restoration.
- Recommended Usage: 0.12% in leave-on products (scalp serums, treatments); 0.5% in rinse-off (shampoos, conditioners).
- Key Benefits: Targets dandruff root causes, calms redness/irritation, and promotes a healthier, less prone-to-flakes scalp.
These bioactive advantages position sclareolide as a bridge between olfactive luxury and science-backed wellness in modern formulations.
Sustainable Biosynthetic Production: Overcoming Traditional Limitations
Historically derived from clary sage (Salvia sclarea), sclareolide extraction faces low yields, high costs, seasonal variability, and environmental concerns. Chemical synthesis alternatives often involve non-green processes.
Genvera Labs employs advanced bio-based manufacturing—leveraging microbial fermentation and synthetic biology—to deliver:
- High-purity ≥98% output with batch consistency
- Scalable, year-round supply without plant dependency
- Eco-friendly process eliminating hazardous chemicals and reducing ecological impact
- Cost-effective efficiency aligned with clean-label and sustainability demands from premium brands
This green platform supports ethical sourcing and meets surging demand for natural-origin, high-performance ingredients in fragrance, skincare, and hair care markets.
Sclareolide Specifications Overview
- Product Name: Sclareolide
- CAS Number: 564-20-5
- Molecular Formula: C₁₆H₂₈O
- Purity: ≥98%
- Natural Index: 100%
- Key Applications: Fine Fragrances & Fixatives, Luxury Cosmetics & Personal Care, Functional Skincare (Brightening/UV Protection), Hair & Scalp Care (Anti-Dandruff/Soothing)
Genvera Labs' Competitive Edge
- Unmatched Purity — ≥98% maximizes bioactivity, fragrance impact, and formulation stability.
- Sustainable Bio-based Manufacturing — Fermentation replaces traditional extraction, supporting green chemistry and ethical supply chains.
- Customizable Supply Solutions — Flexible specifications, scalable volumes, and expert formulation guidance tailored to your needs—whether enhancing a signature amber perfume, developing brightening serums, or creating microbiome-friendly scalp solutions.
As consumers demand multifunctional, sustainable ingredients that blend captivating scent with tangible skin and hair benefits, sclareolide delivers unmatched versatility. Its woody-amber signature, superior fixation, and clinically supported bioactives make it essential for innovative, premium products.
Ready to incorporate high-purity, biosynthesized sclareolide into your next fragrance, skincare, or hair care innovation? Contact Genvera Labs for samples, technical data, bulk supply, or custom support today.