For centuries, ambergris—the legendary "floating gold" harvested from sperm whales—has enchanted perfumers with its mesmerizing, long-lasting fragrance: rich, sweet, warm, animalic, marine, and velvety, capable of lingering for months while amplifying diffusion and depth in compositions. Prized by royalty and nobility, its scarcity, ethical concerns, and international protections under endangered species regulations have made natural ambergris virtually unobtainable for modern use.
Enter (-)-Ambroxide (also known as Ambroxan, Ambrox, Ambrofix, or Ambroxide, CAS 6790-58-5), the principal aromatic compound identified in natural ambergris and universally acclaimed as the premier synthetic substitute. This chiral molecule replicates the iconic "ambergris effect" with unmatched fidelity: a powerful, radiant woody-amber signature blended with dry ambergris warmth, clean woody cedar facets, subtle marine saltiness, powdery musk, sweet earthy undertones, and a delicate animalic tonality—often described as balsamic, velvety, slightly tobacco-like, and intensely diffusive.
With exceptional fixative power and radiance, (-)-Ambroxide dramatically enhances fragrance longevity, creates an elegant velvety trail, and elevates entire compositions—making it indispensable in luxury fine fragrances, niche perfumes, and high-end creations.
The Signature Profile and Versatile Applications of (-)-Ambroxide
(-)-Ambroxide delivers the authentic ambergris character in a clean, ethical form:
- In fine perfumery & luxury fragrances: Provides strong base-note amber-woody depth in oriental, amber, woody, marine, fougère, and gourmand accords; excels as a fixative and diffuser, boosting projection and substantivity across top, heart, and dry-down.
- In personal care & cosmetics: Gentle and non-irritating, ideal for skin creams, lotions, hair care, shampoos, soaps, talcum powders, deodorants, and fabric conditioners—imparts sophisticated warmth and lasting scent without sensitization risks.
- In tobacco & flavor applications: Harmonizes with cigarette and Oriental tobacco blends, adding rich, velvety depth, woody nuances, and subtle sweetness to enhance complexity and sophistication in tobacco flavor systems.
Its molecular formula C₁₆H₂₈O and ultra-high ≥99% purity ensure minimal impurities, maximum potency, and consistent performance—surpassing many commercial grades for cleaner profiles and superior results.
Pioneering Full-Chain Biosynthetic Production: A Greener Future for Ambroxide
Traditional production of Ambroxide relied on scarce natural precursors like sclareol from clary sage, followed by multi-step chemical synthesis—often involving complex processes, variable quality, and environmental concerns.
Genvera Labs has pioneered an innovative, full-chain biosynthetic pathway using cutting-edge synthetic biology and microbial fermentation. This seamless, eco-friendly sequence transforms sclareol → sclareolide → Ambroxide:
- Efficient microbial process for high-yield conversion
- Consistent ≥99% purity and batch-to-batch reliability
- Superior scalability without raw material shortages
- Zero hazardous byproducts and dramatically reduced environmental impact
This breakthrough delivers a reliable, cost-effective, sustainable supply—empowering fragrance houses, personal care brands, cosmetics manufacturers, and tobacco flavor developers with an ethical, high-performance alternative aligned with global sustainability trends.
(-)-Ambroxide Specifications Overview
- Product Name: (-)-Ambroxide
- CAS Number: 6790-58-5
- Molecular Formula: C₁₆H₂₈O
- Purity: ≥99%
- Key Applications: Flavors & Fragrances, Fine Perfumery & Luxury Fragrances
Genvera Labs' Competitive Edge
- Unmatched Purity — ≥99% maximizes diffusive radiance, fixative strength, and clean olfactory impact.
- Sustainable Bio-based Manufacturing — Full biosynthetic chain eliminates traditional limitations, supporting green chemistry and ethical sourcing.
- Customizable Supply Solutions — Flexible specifications, scalable volumes, and expert formulation support tailored to your needs—whether crafting iconic amber-led perfumes, enhancing personal care lines, or enriching tobacco blends.
In an era where luxury meets responsibility, (-)-Ambroxide from Genvera Labs offers the ultimate ambergris experience: timeless elegance, exceptional performance, and a truly sustainable footprint.
Ready to infuse your next luxury fragrance, personal care, or flavor creation with premium, biosynthesized (-)-Ambroxide? Contact Genvera Labs for samples, technical data, bulk inquiries, or custom collaboration today.
